Buy MDAI 5,6-methylenedioxy-2-aminoindane Powder

What is MDAI Powder?

MDAI (5,6-methylenedioxy-2-aminoindane) is a drug developed in the 1990s by a team led by David E. Nichols at Purdue University. It acts as a non-neurotoxic and highly selective serotonin releasing agent (SSRA) in vitro and produces entactogen effects in humans.

MDAI has been advertised as a designer drug. It started to be sold online from around 2007, but reached peak popularity between about 2010–2012, after bans on mephedrone came into effect in various countries.

Internet-sourced products claimed to be MDAI have been shown variously to contain mephedrone or other substituted cathinone derivatives, and mixed compositions of inorganic substances, while generally containing no MDAI.

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The number of internet searches for MDAI has been considerably higher in the UK compared to Germany and the USA. MDAI is only non-neurotoxic in isolation but may become neurotoxic when mixed with other drugs.

 

Three deaths were linked to MDAI use in the UK during 2011–2012, all involving symptoms consistent with serotonin syndrome. Two of these also involved other drugs while one death appeared to be from MDAI alone.

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It acts as a selective serotonin and norepinephrine releasing agent (SNRA).The drug shows greatly reduced serotonergic neurotoxicity in comparison to MDMA in animals, although it still shows weak capacity for neurotoxicity with chronic use or in combination with amphetamine.

MDAI was developed in the 1990s by a team led by David E. Nichols at Purdue University. It has been encountered as a designer drug and has been used recreationally with reported street names such as “sparkle” and “mindy”.

In addition to its recreational use, there has been interest in MDAI for potential use in medicine, for instance in drug-assisted psychotherapy.

Scientific research

MDAI and other similar drugs have been widely used in scientific research, as they are able to replicate many of the effects of MDMA, but without causing the serotonergic neurotoxicity associated with MDMA and certain related drugs. No tests have been performed on cardiovascular toxicity